Scientific research
Our Research

Research & Clinical Trials

Explore our therapeutic research areas and ongoing clinical trials advancing next-generation treatments across critical medical domains.

Therapeutic Areas

Oncology

Oncology

2 trials

Our oncology research program focuses on developing novel targeted therapies and immunotherapeutic approaches for solid tumors and hematological malignancies. Through precision medicine and advanced biomarker-driven trial designs, we aim to improve patient outcomes across a wide range of cancer types.

Immunology

Immunology

2 trials

Our immunology division investigates the complex mechanisms of immune response to develop breakthrough treatments for autoimmune disorders, allergic diseases, and immune deficiencies. We leverage cutting-edge monoclonal antibody technology and immune checkpoint modulation.

Neuroscience

Neuroscience

2 trials

MedHubs neuroscience research addresses critical unmet needs in neurological and psychiatric disorders. Our pipeline includes novel treatments for neurodegenerative diseases, mood disorders, and chronic pain through innovative mechanisms of action.

Infectious Diseases

Infectious Diseases

2 trials

Our infectious disease research combats emerging pathogens and antibiotic-resistant bacteria through next-generation antivirals, novel antibiotics, and vaccine platforms. We maintain rapid response capabilities for pandemic preparedness and global health security.

Rare Diseases

Rare Diseases

2 trials

The rare diseases program at MedHubs is dedicated to developing transformative therapies for patients with genetic and orphan diseases. Using gene therapy, enzyme replacement, and RNA-based approaches, we bring hope to underserved patient populations.

AI-Driven Drug Discovery

AI-Driven Drug Discovery

2 trials

Our AI-driven drug discovery platform combines machine learning, molecular simulations, and vast chemical libraries to accelerate the identification and optimization of novel drug candidates. This approach significantly reduces development timelines and improves success rates.

Clinical Trials

Phase I
Not Yet Recruiting
AI-Driven Drug Discovery

MH-AI-501: AI-Designed Kinase Inhibitor in Solid Tumors

A Phase I dose-finding study of a first-in-class kinase inhibitor identified through AI-driven molecular screening. This trial evaluates safety, tolerability, and recommended Phase II dose in patients with advanced solid tumors.

Started: Jul 2025
Phase I
Recruiting
Rare Diseases

MH-RARE-101: Gene Therapy for Spinal Muscular Atrophy Type II

A single-arm, open-label Phase I/II study to evaluate the safety and preliminary efficacy of an AAV9-based gene therapy vector in pediatric patients with Spinal Muscular Atrophy Type II.

Started: Feb 2025
Phase II
Completed
Infectious Diseases

MH-INF-402: Phase II Broad-Spectrum Antiviral for Respiratory Viruses

A randomized, placebo-controlled Phase II study evaluating the efficacy and safety of a novel broad-spectrum antiviral agent for the treatment of acute respiratory viral infections including influenza and RSV.

Started: Sep 2023Est. Completion: Apr 2025
Phase I
Active
Neuroscience

MH-NEURO-104: Phase I/II Study of BDNF Mimetic in Early-Stage Alzheimer's Disease

A first-in-human, dose-escalation study evaluating the safety, tolerability, pharmacokinetics, and preliminary efficacy of a novel BDNF mimetic compound in patients with early-stage Alzheimer's disease and confirmed amyloid pathology.

Started: Jan 2025Est. Completion: Mar 2027
Phase II
Recruiting
Immunology

MH-IMM-205: Phase II Evaluation of Novel Anti-IL-17 Antibody in Psoriatic Arthritis

An open-label, multi-center Phase II study assessing the efficacy, safety, and pharmacokinetics of a novel anti-IL-17 monoclonal antibody in patients with moderate-to-severe psoriatic arthritis who have inadequate response to conventional DMARDs.

Started: Jun 2024Est. Completion: Dec 2026
Phase III
Active
Oncology

MH-ONC-301: Phase III Study of MedHubs Targeted Therapy in Advanced Non-Small Cell Lung Cancer

A randomized, double-blind, placebo-controlled Phase III study evaluating the efficacy and safety of MH-ONC-301 in combination with standard chemotherapy for patients with advanced NSCLC harboring specific molecular alterations.

Started: Mar 2024Est. Completion: Jun 2027
Phase I
Not Yet Recruiting
AI-Driven Drug Discovery

MH-AI-501: AI-Designed Kinase Inhibitor in Solid Tumors

A Phase I dose-finding study of a first-in-class kinase inhibitor identified through AI-driven molecular screening. This trial evaluates safety, tolerability, and recommended Phase II dose in patients with advanced solid tumors.

Started: Jul 2025
Phase I
Recruiting
Rare Diseases

MH-RARE-101: Gene Therapy for Spinal Muscular Atrophy Type II

A single-arm, open-label Phase I/II study to evaluate the safety and preliminary efficacy of an AAV9-based gene therapy vector in pediatric patients with Spinal Muscular Atrophy Type II.

Started: Feb 2025
Phase II
Completed
Infectious Diseases

MH-INF-402: Phase II Broad-Spectrum Antiviral for Respiratory Viruses

A randomized, placebo-controlled Phase II study evaluating the efficacy and safety of a novel broad-spectrum antiviral agent for the treatment of acute respiratory viral infections including influenza and RSV.

Started: Sep 2023Est. Completion: Apr 2025
Phase I
Active
Neuroscience

MH-NEURO-104: Phase I/II Study of BDNF Mimetic in Early-Stage Alzheimer's Disease

A first-in-human, dose-escalation study evaluating the safety, tolerability, pharmacokinetics, and preliminary efficacy of a novel BDNF mimetic compound in patients with early-stage Alzheimer's disease and confirmed amyloid pathology.

Started: Jan 2025Est. Completion: Mar 2027
Phase II
Recruiting
Immunology

MH-IMM-205: Phase II Evaluation of Novel Anti-IL-17 Antibody in Psoriatic Arthritis

An open-label, multi-center Phase II study assessing the efficacy, safety, and pharmacokinetics of a novel anti-IL-17 monoclonal antibody in patients with moderate-to-severe psoriatic arthritis who have inadequate response to conventional DMARDs.

Started: Jun 2024Est. Completion: Dec 2026
Phase III
Active
Oncology

MH-ONC-301: Phase III Study of MedHubs Targeted Therapy in Advanced Non-Small Cell Lung Cancer

A randomized, double-blind, placebo-controlled Phase III study evaluating the efficacy and safety of MH-ONC-301 in combination with standard chemotherapy for patients with advanced NSCLC harboring specific molecular alterations.

Started: Mar 2024Est. Completion: Jun 2027